Tyrosine Kinase Mutations in Myeloproliferative Neoplasms
New policy. "JAK2 tyrosine kinase and MPL mutation testing may be considered medically necessary in the diagnosis of patients presenting with clinical, laboratory, or pathological findings suggesting classic forms of myeloproliferative neoplasms (MPN), that is, polycythemia vera (PV), essential thrombocythemia (ET), or primary myelofibrosis (PMF). JAK2 tyrosine kinase and MPL mutation testing may be considered investigational in all other circumstances" Notification given July 19, 2011. Policy implemented October 25, 2011.